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Calcium
Supplement Guide Robust evidence

Calcium

In 1808, a young Humphry Davy hooked his new battery to a paste of "lime," boiled off the mercury, and—against all expectations—pulled a silvery metal from...

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Trimethylglycine (TMG, betaine)
Supplement Guide Promising evidence

Trimethylglycine (TMG, betaine)

In the 1860s, a sugar chemist sifting through beet molasses pulled out a strange, crystalline compound. Carl Scheibler named it after the plant...

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Papain
Supplement Guide Promising evidence

Papain

You're holding a green papaya. Inside its milky sap lives an invisible blade—papain—that can soften a steak, clear a wound, calm a cramping gut, and, in the...

Papain

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