Betaine hydrochloride
Found in 51 products 5 forms available Trending for: liver detox, methylation support
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Supplement Guide Promising evidence
Betaine (trimethylglycine; "TMG")
Picture a 19th-century sugar factory. Amid the steam and sweet molasses, a German chemist isolates a peculiar, salt-like substance from beets. He names it for...

Comparison Promising evidence
TMG (betaine anhydrous; trimethylglycine) vs Betaine HCl (betaine hydrochloride)
Pick TMG if your goal is methylation/homocysteine support; pick Betaine HCl only for short-term gastric acid support (e.g., with pH-dependent drugs) and...
Understanding Betaine hydrochloride
Reported benefits
→Supports digestive comfort by helping to increase stomach acidity, promoting more efficient digestion.
→May support liver-related detox pathways through betaine’s role in methylation-related processes.
→Supports metabolic health by contributing to methylation-related cellular functions.
Dosage Guide
25mg
Low
100mg
Standard
326.5mg
Therapeutic
• Most products contain 25-100mg
• Therapeutic dose: 100-326.5mg
Forms & Absorption
Betaine Hydrochloride
Standard form
559 products
Betain HCl
Standard form
10 products
Betain HCL
Standard form
3 products
Betaine Hydrochloride; Powder
Standard form
2 products
Betaine Hydrochloride (HCl)
Standard form
1 products
Timing & Usage
Based on analyzing 2,228 products with Betaine hydrochloride
Best taken:With meals
With food:24% recommend with food, 6% on empty stomach
Spacing:5% show drug interactions - consider spacing from medications
Works Well With
Top Products

High Potency Betaine HCl with Pepsin 650 mg
Solaray • Capsule
$31.90

Advanced Digestive Enzymes
Thorne • Capsule
$53.00

Betaine Hydrochloride 600 mg With Pepsin
Country Life • Tablet or Pill
$15.49

HCL Breakthrough
BiOptimizers • Capsule
$27.99