Search Results for "Pregnenolone"

Pregnenolone is a neurosteroid your body makes from cholesterol, upstream of hormones like progesterone, DHEA, and cortisol. In the brain it can convert into compounds that nudge GABA and NMDA receptors—systems tied to mood, stress, pain perception, and thinking. Think of it as a precursor molecule that may fine‑tune neural signaling rather than a classic stimulant or sedative.

• Improve mood in bipolar depression (adjunctive use)
• Reduce anxiety and stress feelings
• Support cognitive function and functional capacity (adjunct to antipsychotics)
• Aid recovery/function in chronic low back pain

Evidence