Suplmnt
Evidence Level: robust

Pick whey if you want the most leucine and lean-mass support per scoop and you tolerate dairy; pick plant protein if you're vegan/dairy-sensitive—just use a blend or slightly larger dose to match leucine.

Both build muscle and aid recovery; when protein and leucine are matched, outcomes are often similar. Whey has higher DIAAS and leucine density (fewer scoops for the same anabolic signal), while plant options excel for vegan/dairy-free needs and can achieve comparable results with blends or higher doses. Choose certified products to reduce contaminant risk and tailor by tolerance and diet.^[1][2][3][6][7][8][10][11][12]

The Comparison

Standardization: Typically 70–80% protein (concentrate), ≥90% (isolate), variable for hydrolysate; leucine ~10–12% of protein; DIAAS ~1.0–1.25 depending on form.

Dosage: 20–40 g/serving, targeting ~2–3 g leucine; 1.4–2.0 g/kg/day total protein for active people.

Benefits

  • Highest-quality amino acid profile and fast digestion
  • More leucine per scoop to reach MPS threshold easily
  • Extensive clinical evidence for strength/lean mass support

Drawbacks

  • Contains dairy; lactose varies by form
  • Not suitable for milk allergy
  • Some concentrates include more carbs/fat

Safety:WPI typically ~0.5–1.0% lactose; concentrates (e.g., WPC80) ~4–8% lactose. Choose third-party certified products to minimize contaminant risk.

Standardization: Commonly pea, soy, rice; often blended to complement amino acids. DIAAS generally lower than dairy (e.g., pea isolate ~0.82; soy isolate ~0.90).

Dosage: 25–45 g/serving (higher end may be needed to match whey's leucine); 1.4–2.0 g/kg/day total protein for active people.

Benefits

  • Dairy-free/vegan; usually lactose-free
  • Can match outcomes if total protein/leucine are equated
  • Often higher in iron; blends improve amino profile

Drawbacks

  • Lower leucine and DIAAS per gram—may need larger dose
  • Some powders report higher heavy-metal findings (brand-dependent)
  • Soy or legume sensitivities for some users

Safety:Prefer brands with rigorous third-party testing (NSF Certified for Sport/Informed) to mitigate contaminant variability; consider blends or added leucine to reach targets.

Head-to-Head Analysis

Efficacy for muscle/strength Critical

Winner:Whey protein (concentrate/isolate/hydrolysate) Importance: high

Meta-analyses and RCTs show animal proteins (incl. whey) slightly favor lean mass vs plant, though strength gains are often similar when total protein is sufficient; pea vs whey RCTs show comparable results when matched.^[2][3][5][6]

Leucine density and per-serving dose Critical

Winner:Whey protein (concentrate/isolate/hydrolysate) Importance: high

Whey provides more leucine per gram (≈2.7 g leucine in 25 g whey), reaching the 0.7–3 g target more easily; many plant isolates require ~33–40+ g protein to match leucine.^[1][9][11]

Digestibility/bioavailability (DIAAS/PDCAAS)

Winner:Whey protein (concentrate/isolate/hydrolysate) Importance: medium

Whey typically scores ≈1.0+ on DIAAS; pea/soy are lower (≈0.82–0.90). Blends can improve plant scores but still trail high-quality dairy proteins.^[7][12][13]

Onset/time-to-effect (post-exercise MPS)

Winner:Whey protein (concentrate/isolate/hydrolysate) Importance: medium

Fast-digesting whey elevates EAAs and MPS more than soy in acute trials; pea shows similar recovery markers vs whey in some settings but evidence is less consistent.^[4][6]

Tolerability for lactose/dairy avoidance Critical

Winner:Plant protein (pea/soy/rice blends) Importance: high

Plant proteins are dairy-free; whey isolate has minimal lactose but still milk-derived and unsuitable for milk allergy.^[10]

Safety/contaminants and label assurance Critical

Winner:Tie Importance: high

Recent testing reports higher heavy-metal findings on average in plant powders, but results vary by brand; third-party certification (e.g., NSF Certified for Sport) mitigates risk for both.^[7][8][14][15][16]

Cost/value per effective dose

Winner:Whey protein (concentrate/isolate/hydrolysate) Importance: medium

Because whey has higher leucine/DIAAS per gram, fewer grams may be needed to hit effective leucine—improving cost per effective dose; some plant users compensate with larger servings or blends.^[1][9]

Dietary fit and versatility

Winner:Plant protein (pea/soy/rice blends) Importance: medium

Plant proteins serve vegan diets and dairy sensitivities and can be blended to achieve completeness; whey is not suitable for vegan diets.^[7][12]

Common Questions

How much protein should I take per serving?

20–40 g of a high-quality protein with ~0.7–3.0 g leucine per serving, spaced every 3–4 hours, fits most active people.^[1][11]

Can plant protein really build muscle as well as whey?

Yes—if your total protein/leucine intake is matched (often needing larger servings or blends). Meta-analyses/RCTs show similar strength and comparable lean-mass changes in many contexts.^[2][5]

Is whey isolate lactose-free?

Not entirely, but typically ~0.5–1.0% lactose (often tolerated). Concentrates can have ~4–8%. Milk allergy still requires avoiding whey.^[10]

Do protein powders contain heavy metals?

Some do. A 2025 analysis reported many products—especially some plant/chocolate powders—exceeded certain guidelines. Use NSF/Informed-certified brands to reduce risk.^[14][15][16]

What's the best plant protein type?

Pea-rice or soy blends improve amino acid completeness and can reach leucine targets with 30–40+ g servings or added leucine.^[7][9][12]

Which Should You Choose?

Maximizing muscle gain with minimal powder/scoops

Choose:Whey protein (concentrate/isolate/hydrolysate)

Higher leucine and DIAAS per gram speeds hitting MPS targets with 20–30 g doses.^[1][2][9][12]

Vegan or dairy-free lifestyle, or milk allergy

Choose:Plant protein (pea/soy/rice blends)

Plant proteins are inherently dairy-free; use pea-rice/soy blends or added leucine to match whey's anabolic signal.^[7][12]

Lactose intolerance with mild symptoms

Choose: Either option

Whey isolate is ~0.5–1.0% lactose and may be tolerated; plant proteins avoid lactose entirely—choose based on tolerance.^[10]

Cutting/weight management with high protein targets

Choose:Whey protein (concentrate/isolate/hydrolysate)

Whey's higher quality per calorie helps meet per-meal leucine with fewer calories and grams; evidence supports higher protein intakes for composition during energy deficit.^[1]

Concern about contaminants (heavy metals/banned substances)

Choose: Either option

Risk varies by brand; select NSF Certified for Sport or Informed-certified whey or plant products to ensure label accuracy and contaminant controls.^[14][15][16]

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