Trimethylglycine
Found in 66 products 5 forms available Trending for: methylation cycle, liver detox, athletic performance
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Supplement Guide Promising evidence
Magnesium
On a summer day in 1618, a farmer in Epsom, England led his cows to a spring. They refused to drink—too bitter. But when he splashed the water on a rash, it...
Supplement Guide Promising evidence
Trimethylglycine (TMG, betaine)
In the 1860s, a sugar chemist sifting through beet molasses pulled out a strange, crystalline compound. Carl Scheibler named it after the plant...
Matches Trimethylglycine
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Best for Mood (mild Depression Or Anxiety)
Silexan (oral lavender) 80–160 mg/day – best for anxiety-driven low mood [^1][^2]
Understanding Trimethylglycine
Reported benefits
→Supports healthy liver function and detox pathways
→Promotes healthy homocysteine levels via methylation
→May support athletic performance and exercise endurance
→Supports energy production during physical activity
Dosage Guide
25mg
Low
100mg
Standard
250mg
Therapeutic
• Most products contain 25-100mg
• Therapeutic dose: 100-250mg
Forms & Absorption
Betaine
Standard form
508 products
Betaine HCl
Standard form
504 products
Trimethylglycine
Standard form
282 products
Betaine Nitrate
Standard form
41 products
TMG
Standard form
29 products
Timing & Usage
Based on analyzing 8,784 products with Trimethylglycine
Best taken:With meals
With food:31% recommend with food, 3% on empty stomach
Spacing:<1% show interactions
Works Well With
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