Melatonin
Best for
Increase deep, restorative sleep
Large effect, needs confirmation · 0.3–9 mg/day for 4–12 weeks · 2 studies , n=24
101 papers · 10 claims · 203 outcomes scored · 9 positive
Evidence summary
Evidence summary
Proven benefitMelatonin provides proven benefit for falling asleep faster and easing jet lag in adults with sleep-timing problems, while benefits are smaller for total sleep time and nighttime awakenings.
Outcomes
What melatonin actually does, by outcome
Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.
More time in the sleep stages where your body does its heaviest repair.
Shrinks the gap between hitting the pillow and actually sleeping.
Fewer wake-ups and more unbroken hours of real rest.
Gets your internal clock back on local time so you lose fewer days.
Quiets the nervous-system overdrive that keeps you wired at bedtime.
Deeper, less interrupted nights that leave you recharged by morning.
More genuine sleep hours so your body finishes its repair cycles.
Less grogginess, more energy from the moment you open your eyes.
Sharper reaction times and steadier steering when driving fatigue sets in.
Forms & standardisation
Most human trials use oral melatonin in straightforward tablets, capsules, or prolonged-release tablets—not flashy multi-ingredient sleep blends.23 If your goal is falling asleep faster, a simple immediate-release product fits melatonin's job as a fast "night has started" signal; prolonged-release versions aim to mimic the body's slower overnight drip.12 Pick a label that clearly lists the exact milligrams per serving so you can actually match a studied dose.
Risk profile
Adverse events and known drug interactions
Safety events
Drug interactions
Co-studied with
Supplements that share evidence with melatonin
Frequently asked
Common questions
How much melatonin should you take for sleep?
Does melatonin actually work for jet lag?
Why does melatonin help me fall asleep but not keep me asleep?
How long before bed should you take melatonin?
Can you take melatonin every night?
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Sources
Generated May 11, 2026