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Nicotinamide Adenine Dinucleotide

Nicotinamide Adenine Dinucleotide

Doesn't appear to help

Steady your blood sugar levels

May have slight negative effect · 100–6000 mg/day · 1 meta-analysis , n=4k

2 papers · 1 claim · 10 outcomes scored

Outcomes

What nicotinamide adenine dinucleotide actually does, by outcome

Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.

Outcome Effect Evidence Dose Weeks Rank
Steady your blood sugar levels May have slight negative effect
small 		1 meta-analysis n=4.0k Meta-analyzed 100–6000 mg — —

Risk profile

Adverse events and known drug interactions

Safety events

Gastrointestinal symptoms (bloating, gas, indigestion/upper abdominal discomfort) mild
flushing
gastrointestinal upset

Co-studied with

Supplements that share evidence with nicotinamide adenine dinucleotide

Sources

  1. 1. Effects of NAD+ precursor supplementation on glucose and lipid metabolism in humans: a meta-analysis. (2022) ↑
  2. 2. Randomized crossover clinical trial of coenzyme Q10 and nicotinamide riboside in chronic kidney disease. (2023) ↑

Generated August 14, 2026

Related

More evidence for Nicotinamide Adenine Dinucleotide

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