The supplement, ranked by the evidence.

The 10 Best Supplements for Memory, Ranked by Evidence

Bacopa leads our evidence-ranked list of memory supplements, backed by multiple trials showing real improvements in recall and learning. See all 10 picks.

May 9, 2026 · #1 Bacopa · 10 ranked · 148 trials

Best Supplements for Period Cramps, Ranked by Clinical Evidence

Fennel tops our evidence-ranked list of period cramp supplements. We scored 20 options across 17 dysmenorrhea trials to find what actually works.

Apr 4, 2026 · #1 Fennel · 7 ranked · 17 trials

Best Supplements for Blood Sugar, Ranked by Clinical Evidence

Fenugreek tops our evidence-ranked list of blood sugar supplements, followed by inulin and green tea. We scored 152 supplements across 420 trial endpoints.

Apr 4, 2026 · #1 Fenugreek · 7 ranked · 420 trials

Best Supplements to Lower LDL and Total Cholesterol

Phytosterols top our evidence-ranked list of cholesterol supplements. We scored 166 supplements across 441 trials for LDL and total cholesterol.

Apr 4, 2026 · #1 Phytosterols (Plant Sterols and Stanols) · 6 ranked · 441 trials

Best Supplements for Brain Fog and Mental Clarity, Ranked by Evidence

Curcumin tops our evidence-ranked list of supplements for brain fog and mental clarity. We scored 97 supplements across 194 trials to find the 4 that actually work.

Apr 4, 2026 · #1 Curcumin (Turmeric Extract) · 4 ranked · 194 trials

Best Supplements for Migraines and Headaches, Ranked by Clinical Evidence

Melatonin tops our evidence-ranked list of migraine supplements. We scored 29 supplements across 16 trials measuring headache frequency, severity, and duration.

Apr 4, 2026 · #1 Melatonin · 4 ranked · 16 trials

The 7 Supplements That Actually Help You Catch Fewer Colds

Echinacea purpurea tops our evidence-ranked list of cold-prevention supplements, followed by vitamin C and vitamin D. We scored 20 supplements across 31 trials.

Apr 4, 2026 · #1 Echinacea (E. purpurea) · 7 ranked · 31 trials

Best Supplements for Skin Hydration, Ranked by Clinical Evidence

Collagen peptides top our evidence-ranked list of skin hydration supplements, backed by 13 trials and three meta-analyses. Oral HA and astaxanthin follow.

Apr 4, 2026 · #1 Collagen Peptides · 3 ranked · 29 trials

Best Supplements for Fat Loss, Ranked by Clinical Evidence

Green tea extract tops our evidence-ranked list of fat loss supplements. We scored 70 supplements across 102 trials. Most popular fat burners don't work.

Apr 4, 2026 · #1 Green Tea Extract (EGCG) · 7 ranked · 102 trials

Best Supplements for Depression, Ranked by Clinical Evidence

Omega-3 (EPA) tops our evidence-ranked list of 77 depression supplements. Curcumin, magnesium, and St. John's Wort round out the top tier, backed by pooled trial data.

Apr 4, 2026 · #1 Omega-3 (EPA) · 8 ranked · 130 trials

Best Supplements for Testosterone, Ranked by Evidence

Tongkat Ali tops our evidence-ranked list of testosterone supplements, followed by ashwagandha. We scored 23 supplements across 40 trials. See which ones work.

Apr 4, 2026 · #1 Tongkat Ali (Eurycoma longifolia) · 7 ranked · 40 trials

Best Supplements for Fatty Liver Disease (NAFLD), Ranked by Evidence

Berberine tops our evidence-ranked list of fatty liver supplements. 26 supplements scored across 29 trials measuring liver fat directly.

Apr 4, 2026 · #1 Berberine · 7 ranked · 29 trials

Best Supplements for Blood Pressure, Ranked by Clinical Evidence

Lycopene tops our evidence-ranked list of blood pressure supplements, followed by taurine and quercetin. We scored 130 supplements across 311 endpoints.

Apr 4, 2026 · #1 Lycopene · 9 ranked · 311 trials

Best Supplements for Anxiety, Ranked by Clinical Evidence

Lavender oil capsules (Silexan) top our evidence-ranked list of anxiety supplements — 6 picks backed by clinical trials, plus 5 popular options that don't hold up.

Apr 4, 2026 · #1 Lavender Oil (Silexan) · 6 ranked · 83 trials

Best Supplements to Stay Asleep Through the Night

Evidence-ranked supplements for staying asleep through the night. Omega-3 leads for reducing wake-ups, plus melatonin, ashwagandha, saffron, and valerian reviewed across 48 trials.

Apr 4, 2026 · #1 Omega-3 · 10 ranked · 48 trials

Best Supplements for Arthritis and Joint Pain, Ranked by Clinical Evidence

Turmeric leads the evidence for arthritis pain relief. We scored 39 supplements across 73 trials to rank what actually works for joint pain and stiffness.

Apr 4, 2026 · #1 Turmeric (Curcumin Extract) · 9 ranked · 73 trials

Best Supplements for Daily Stress Relief, Ranked by Clinical Evidence

Lavender oil (Silexan) tops our evidence-ranked list for daily stress, followed by ashwagandha and lemon balm. We analyzed 100 trials to find what actually works.

Apr 4, 2026 · #1 Lavender Oil (Silexan) · 7 ranked · 100 trials

Best Supplements to Ease Neuropathy Pain and Numbness (2026)

Evidence-based ranking of OTC supplements for neuropathy pain and numbness, using 25 clinical trials across diabetic, chemo, and broader nerve symptoms.

Apr 4, 2026 · #1 Alpha Lipoic Acid · 10 ranked · 25 trials

The 10 Supplements With Real Evidence for Faster Thinking

Theanine, turmeric, and bacopa top the evidence for faster thinking and quicker reactions. 70 supplements scored across 114 trials.

Apr 3, 2026 · #1 Lithium · 10 ranked · 114 trials

Best Supplements for Deep, Restful Sleep (2026)

Evidence-ranked sleep supplements from 5,887 clinical trials across 546 ingredients. Melatonin, ashwagandha, saffron, magnesium, valerian, and theanine — what works and what doesn't.

Mar 29, 2026 · #1 Melatonin · 6 ranked · 5887 trials