Evidence map Updated Oct 24, 2026

Stress

Explore clinical evidence across the ways people experience stress, anxiety, and recovery.

69 ingredients · 6 outcomes · 112 trials

Evidence map

Evidence across stress

Benefit Mixed / early No clear benefit Harm Not studied

Stress evidence map Lower perceived stress

Stress Ingredient	Lower perceived stress	Fewer anxiety symptoms	More calmness and confidence	Lower cortisol levels	Stress hormone balance, the body's stress hormones	Daily cortisol rhythm, a hormone pattern
5-HTP
Affron
American Ginseng (Panax quinquefolius)
Ashwagandha
Bacognize
BacoMind
Bacopa
BCM-95
Cannabidiol
Cannabinoids
Cannabis / Marijuana
Chamomile
Cocoa / Cacao
Creatine
Creatine Malate
Creatine nitrate
Curcumin
CurcuWIN
English Lavender
Eurycoma Longifolia
Ginsenosides
Gotu Kola
Lion's Mane
Himalayan Rhubarb
Holy Basil
Hops
Inositol
Kava kava
KSM-66
Lactobacillus helveticus
Lemon balm
Lemon Verbena
Licorice
Lithium
Lithium Aspartate
Longvida
Magnesium
Magnesium Aspartate
Magnesium Chloride
Magnesium Citrate
Magnesium Creatine
Magnesium Gluconate
Magnesium Glycinate
Magnesium hydroxide
Magnesium L-Threonate
Magnesium Oxide
Magnolia
Melatonin
Meriva
Mushrooms
Oriental Ginseng (Panax ginseng)
Ornithine
Passionflower
Phosphatidylserine
PQQ
Reishi mushroom
Rhodiola
Rosmarinic Acid
Saffron
Satiereal
Sensoril
Shoden
Synapsa
Tetrahydrocannabinol
Theanine
Theracurmin
L-Tryptophan
L-Tyrosine
Valerian

Evidence map: Stress

Explore clinical evidence across the ways people experience stress, anxiety, and recovery.

Across 69 ingredients and 6 outcomes, this map shows 127 studied pairs covering 112 distinct clinical trials.

Where cells are blank, the (ingredient, outcome) pair has not been studied — 287 such gaps remain on this map.

Methodology

Each studied pair shows its V2 verdict, GRADE certainty, contributing-trial total, and source evidence. Where an audited standardized effect is available, the receipt shows the estimate and its confidence interval when available. Generated 2026-10-24 from 112 contributing trials.

Stress

Evidence across stress

5-HTP × Fewer anxiety symptoms

Affron × Lower perceived stress

Affron × Fewer anxiety symptoms

Affron × Lower cortisol levels

American Ginseng (Panax quinquefolius) × More calmness and confidence

Ashwagandha × Lower perceived stress

Ashwagandha × Fewer anxiety symptoms

Ashwagandha × Lower cortisol levels

Bacognize × Lower perceived stress

Bacognize × Fewer anxiety symptoms

Bacognize × Lower cortisol levels

BacoMind × Lower perceived stress

BacoMind × Fewer anxiety symptoms

BacoMind × Lower cortisol levels

Bacopa × Lower perceived stress

Bacopa × Fewer anxiety symptoms

Bacopa × Lower cortisol levels

BCM-95 × Lower perceived stress

Cannabidiol × Lower perceived stress

Cannabidiol × Fewer anxiety symptoms

Cannabinoids × Fewer anxiety symptoms

Cannabis / Marijuana × Fewer anxiety symptoms

Chamomile × Fewer anxiety symptoms

Cocoa / Cacao × Fewer anxiety symptoms

Creatine × Lower perceived stress

Creatine Malate × Lower perceived stress

Creatine nitrate × Lower perceived stress

Curcumin × Lower perceived stress

CurcuWIN × Lower perceived stress

English Lavender × Lower perceived stress

English Lavender × Fewer anxiety symptoms

Eurycoma Longifolia × Lower perceived stress

Eurycoma Longifolia × Lower cortisol levels

Ginsenosides × Lower perceived stress

Ginsenosides × Fewer anxiety symptoms

Ginsenosides × More calmness and confidence

Gotu Kola × More calmness and confidence

Lion's Mane × Lower perceived stress

Lion's Mane × Fewer anxiety symptoms

Himalayan Rhubarb × Fewer anxiety symptoms

Holy Basil × Lower perceived stress

Holy Basil × Fewer anxiety symptoms

Holy Basil × Lower cortisol levels

Hops × Lower perceived stress

Hops × Fewer anxiety symptoms

Inositol × Fewer anxiety symptoms

Kava kava × Fewer anxiety symptoms

KSM-66 × Lower perceived stress

KSM-66 × Fewer anxiety symptoms

KSM-66 × Lower cortisol levels

Lactobacillus helveticus × Fewer anxiety symptoms

Lactobacillus helveticus × Lower cortisol levels

Lemon balm × Lower perceived stress

Lemon balm × Fewer anxiety symptoms

Lemon balm × Lower cortisol levels

Lemon Verbena × Lower perceived stress

Lemon Verbena × Fewer anxiety symptoms

Licorice × Lower cortisol levels

Lithium × Fewer anxiety symptoms

Lithium Aspartate × Fewer anxiety symptoms

Longvida × Lower perceived stress

Magnesium × Lower perceived stress

Magnesium × Fewer anxiety symptoms

Magnesium × Lower cortisol levels

Magnesium Aspartate × Lower perceived stress

Magnesium Aspartate × Fewer anxiety symptoms

Magnesium Aspartate × Lower cortisol levels

Magnesium Chloride × Lower perceived stress

Magnesium Chloride × Fewer anxiety symptoms

Magnesium Chloride × Lower cortisol levels

Magnesium Citrate × Lower perceived stress

Magnesium Citrate × Fewer anxiety symptoms

Magnesium Citrate × Lower cortisol levels

Magnesium Creatine × Lower perceived stress

Magnesium Gluconate × Lower perceived stress

Magnesium Gluconate × Fewer anxiety symptoms

Magnesium Gluconate × Lower cortisol levels

Magnesium Glycinate × Lower perceived stress

5-HTP

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affron

American Ginseng