Grape
Evidence status
Limited evidence to recommend for any consumer outcome yet.
4 papers · 0 claims · 12 outcomes scored
Risk profile
Adverse events and known drug interactions
Safety events
gastrointestinal discomfort mild
nausea mild
increased stool frequency / abdominal cramps mild
gastrointestinal disorders
gastrointestinal adverse reactions (potential treatment-related)
infection-related events
eye disorders
nervous system disorders
Sources
- 1. Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers. (2021) ↑
- 2. Effect of grape seed proanthocyanidin extract on hard exudates in patients with non-proliferative diabetic retinopathy. (2019) ↑
- 3. Consumption of a polyphenol-rich grape-wine extract lowers ambulatory blood pressure in mildly hypertensive subjects. (2015) ↑
- 4. The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials. (2025) ↑
Generated August 14, 2026