Lactobacillus reuteri

Best for

Reduce diarrhea and recover faster

Proven benefit · 100000000 mg/kg/day/day for 4 weeks · 1 meta-analysis , n=764

3 papers · 2 claims · 3 outcomes scored · 2 positive

Outcomes

What lactobacillus reuteri actually does, by outcome

Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.

Outcome Effect size Evidence Dose Weeks Rank

Reduce diarrhea and recover faster Proven benefit

Fewer loose stools, shorter episodes, and less fluid loss.

2 meta-analyses n=764 100000000 mg/kg/day 4 wk #2/17

32998471·35070839

moderate

2 meta-analyses n=764 Meta-analyzed

100000000 mg/kg/day

4 wk

#2 /17

Ease constipation and stay regular Promising early signal

Softer stools, less straining, and more complete bowel movements.

2 RCTs n=17 100000000 mg/kg/day 2–4 wk #9/18

31952280·32998471

moderate

2 RCTs n=17

100000000 mg/kg/day

2–4 wk

#9 /18

Outcome	Effect	Evidence	Dose	Weeks	Rank
Reduce diarrhea and recover faster Proven benefit	moderate	2 meta-analyses n=764 Meta-analyzed	100000000 mg/kg/day	4 wk	#2/17
Ease constipation and stay regular Promising early signal	moderate	2 RCTs n=17	100000000 mg/kg/day	2–4 wk	#9/18

Risk profile

Adverse events and known drug interactions

Drug interactions

Amoxicillin-Clavulanate minor decreases effect

Pantoprazole minor unknown

Sources

Generated August 14, 2026

Lactobacillus reuteri

What lactobacillus reuteri actually does, by outcome

Adverse events and known drug interactions

More evidence for Lactobacillus reuteri

Bifidobacterium (unspecified)

Colostrum

Glutamine

Lactobacillus rhamnosus

Probiotics

Zinc

Lactobacillus reuteri

More evidence for Lactobacillus reuteri

NewBifidobacterium (unspecified)

NewColostrum

NewGlutamine

NewLactobacillus rhamnosus

NewProbiotics

NewZinc

Bifidobacterium (unspecified)

Colostrum

Glutamine

Lactobacillus rhamnosus

Probiotics

Zinc