Red Clover

Best for

Ease the full menopause symptom load

Likely strong benefit · 43.5–378 mg/day for 52 weeks · 1 meta-analysis , n=646

12 papers · 6 claims · 40 outcomes scored · 2 positive

Outcomes

What red clover actually does, by outcome

Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.

Outcome Effect size Evidence Dose Weeks Rank

Ease the full menopause symptom load Likely strong benefit

Less joint pain, fewer palpitations, and cooler nights.

3 meta-analyses n=646 43.5–378 mg 52 wk #1/13

15084240·33920485·19609225

large

3 meta-analyses n=646 Meta-analyzed I²=96%

43.5–378 mg

52 wk

#1 /13

Improve ovulation and fertility hormones Likely modest benefit

Strengthens the estrogen and progesterone signals that drive ovulation.

1 RCT n=117 43.5 mg 52 wk #3/10

15084240

small

1 RCT n=117

43.5 mg

52 wk

#3 /10

Reduce hot flashes and night sweats Doesn't appear to help

Fewer episodes and milder flushes, especially overnight.

4 meta-analyses n=956 37.1–398 mg 52 wk

15084240·19590458·19609225·33920485

trivial

4 meta-analyses n=956 Meta-analyzed I²=88%

37.1–398 mg

52 wk

—

Build and maintain bone density Not enough research

Keeps mineral packed tightly into hip, spine, and whole-body bone.

1 study n=— 150 mL 12 wk

26265926

—

1 study n=—

150 mL

12 wk

—

Protect bones while breastfeeding Not enough research

Keeps your bone mass intact during the mineral drain of lactation.

1 study n=— 150 mL 12 wk

26265926

—

1 study n=—

150 mL

12 wk

—

Strengthen bones by favoring buildup Not enough research

Your skeleton tips toward building bone faster than it breaks down.

1 study n=— 150 mL 12 wk

26265926

—

1 study n=—

150 mL

12 wk

—

Outcome	Effect	Evidence	Dose	Weeks	Rank
Ease the full menopause symptom load Likely strong benefit	large	3 meta-analyses n=646 Meta-analyzed	43.5–378 mg	52 wk	#1/13
Improve ovulation and fertility hormones Likely modest benefit	small	1 RCT n=117	43.5 mg	52 wk	#3/10
Reduce hot flashes and night sweats Doesn't appear to help	trivial	4 meta-analyses n=956 Meta-analyzed	37.1–398 mg	52 wk	—
Build and maintain bone density Not enough research		1 study n=—	150 mL	12 wk	—
Protect bones while breastfeeding Not enough research		1 study n=—	150 mL	12 wk	—
Strengthen bones by favoring buildup Not enough research		1 study n=—	150 mL	12 wk	—

Buy well

Recommended Red Clover products

Real products that dose Red Clover where the research does, in a clean formulation, from brands we've audited. We only list ones we'd stand behind.

Chosen for adequate Red Clover dosing vs. the studied range, a clean formulation (grade A–C), and independent brand-quality audits. Not sponsored.

Risk profile

Adverse events and known drug interactions

Safety events

endometrial_hyperplasia severe

general_disorder

bleeding_tendency

Drug interactions

Warfarin major increases effect

Drug:Clopidogrel moderate increases concentration

Antithrombotic Agents moderate increases toxicity

Sources

Generated August 14, 2026

Red Clover

What red clover actually does, by outcome

Recommended Red Clover products

Adverse events and known drug interactions

More evidence for Red Clover

DHEA

Diindolylmethane

Black Cohosh

Evening Primrose

Maca

Vitex (unspecified)

Red Clover

Recommended Red Clover products

More evidence for Red Clover

NewDHEA

NewDiindolylmethane

NewBlack Cohosh

NewEvening Primrose

NewMaca

NewVitex (unspecified)

DHEA

Diindolylmethane

Black Cohosh

Evening Primrose

Maca

Vitex (unspecified)