Ellagic Acid

Ellagic Acid

Best for

Lower your blood pressure

Faint early signal · 500 mg/day for 12 weeks · 1 study , n=30

9 papers · 1 claim · 31 outcomes scored · 1 positive

Outcomes

What ellagic acid actually does, by outcome

Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.

Outcome Effect Evidence Dose Weeks Rank
Lower your blood pressure Faint early signal
small
1 RCT n=30 500 mg 12 wk #5/81

Risk profile

Adverse events and known drug interactions

Safety events

gastrointestinal events (bloating, diarrhoea, nausea, abdominal pain, constipation) mild

Sources

  1. 1. Ellagic Acid Effect on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. (2022)
  2. 2. Randomized double blind clinical trial evaluating the Ellagic acid effects on insulin resistance, oxidative stress and sex hormones levels in women with polycystic ovarian syndrome. (2021)
  3. 3. Ellagic acid favorable effects on fatigue, depression and anxiety in patients with multiple sclerosis and moderate disability: A randomized clinical trial. (2025)
  4. 4. Decreased insulin resistance in diabetic patients by influencing Sirtuin1 and Fetuin-A following supplementation with ellagic acid: a randomized controlled trial. (2021)
  5. 5. Ellagic acid effects on disease severity, levels of cytokines and T-bet, RORγt, and GATA3 genes expression in multiple sclerosis patients: a multicentral-triple blind randomized clinical trial. (2023)
  6. 6. Effects of Ellagic Acid on Oxidative Stress Index, Inflammatory Markers and Quality of Life in Patients With Irritable Bowel Syndrome: Randomized Double-blind Clinical Trial. (2022)
  7. 7. Effects of Pomegranate (Punica granatum L.) Peel Extract Supplementation on Markers of Inflammation and Serum Matrix Metalloproteinase 1 in Women With Knee Osteoarthritis: A Randomized Double-Blind Placebo-Controlled Study. (2024)
  8. 8. A randomized double-blind clinical trial investigating the effects of ellagic acid on glycemic status, liver enzymes, and oxidative stress in patients with non-alcoholic fatty liver disease. (2025)
  9. 9. Improving Effect of Ellagic Acid on Sleep Quality and Gastrointestinal Symptoms in Patient With Irritable Bowel Syndrome: Randomized Double-Blind Clinical Trial. (2021)

Generated August 14, 2026

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