Passionflower

Best for

Stay asleep through the night

Large effect, needs confirmation · 600 mg/day for 4 weeks · 1 study , n=65

2 papers · 6 claims · 11 outcomes scored · 6 positive

Outcomes

What passionflower actually does, by outcome

Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.

Outcome Effect size Evidence Dose Weeks Rank

Stay asleep through the night Large effect, needs confirmation

Fewer wake-ups and more unbroken hours of real rest.

1 RCT n=65 600 mg 4 wk #5/15

38646244

large

1 RCT n=65

600 mg

4 wk

#5 /15

Reduce emotional overwhelm Large effect, needs confirmation

The background noise of worry, irritability, and low mood gets quieter.

1 RCT n=65 600 mg 4 wk #1/7

38646244

large

1 RCT n=65

600 mg

4 wk

#1 /7

Fall asleep faster Promising early signal

Shrinks the gap between hitting the pillow and actually sleeping.

1 RCT n=65 600 mg 4 wk #8/19

38646244

moderate

1 RCT n=65

600 mg

4 wk

#8 /19

Improve overall sleep quality Promising early signal

Deeper, less interrupted nights that leave you recharged by morning.

1 RCT n=65 600 mg 4 wk

38646244

moderate

1 RCT n=65

600 mg

4 wk

—

Break the insomnia cycle Faint early signal

Quiets the nervous-system overdrive that keeps you wired at bedtime.

1 RCT n=65 600 mg 4 wk #9/14

38646244

small

1 RCT n=65

600 mg

4 wk

#9 /14

Reduce daily stress Not enough research

Everyday pressure stops running your nervous system hot.

1 RCT n=65 600 mg 4 wk

38646244

trivial

1 RCT n=65

600 mg

4 wk

—

Outcome	Effect	Evidence	Dose	Weeks	Rank
Stay asleep through the night Large effect, needs confirmation	large	1 RCT n=65	600 mg	4 wk	#5/15
Reduce emotional overwhelm Large effect, needs confirmation	large	1 RCT n=65	600 mg	4 wk	#1/7
Fall asleep faster Promising early signal	moderate	1 RCT n=65	600 mg	4 wk	#8/19
Improve overall sleep quality Promising early signal	moderate	1 RCT n=65	600 mg	4 wk	—
Break the insomnia cycle Faint early signal	small	1 RCT n=65	600 mg	4 wk	#9/14
Reduce daily stress Not enough research	trivial	1 RCT n=65	600 mg	4 wk	—

Risk profile

Adverse events and known drug interactions

Safety events

dizziness / drowsiness / confusion mild

somnolence mild

drowsiness

Drug interactions

Anxiolytics minor additive

Sources

Generated August 14, 2026

Passionflower

What passionflower actually does, by outcome

Adverse events and known drug interactions

More evidence for Passionflower

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