Terminalia

Terminalia

Evidence status

Limited evidence to recommend for any consumer outcome yet.

10 papers · 0 claims · 31 outcomes scored

Buy well

Recommended Terminalia products

Real products that dose Terminalia where the research does, in a clean formulation, from brands we've audited. We only list ones we'd stand behind.

Chosen for adequate Terminalia dosing vs. the studied range, a clean formulation (grade A–C), and independent brand-quality audits. Not sponsored.

Risk profile

Adverse events and known drug interactions

Safety events

adrenal_insufficiency / HPA axis suppression severe
Cushingoid features (facial puffiness) moderate
weight_gain moderate
new-onset diabetes mellitus (HbA1c 6.5%) moderate
subclinical_hypothyroidism (TSH 7.19 µIU/mL, anti-TPO positive) mild

Drug interactions

Sertraline major decreases concentration

Sources

  1. 1. Effect of E-OJ-01 on Left Ventricular Ejection Fraction and Myocardial Oxygen Consumption: A Randomized, Double-Blind, Placebo-Controlled Study. (2022)
  2. 2. Effects of Withania somnifera (Ashwagandha) and Terminalia arjuna (Arjuna) on physical performance and cardiorespiratory endurance in healthy young adults. (2010)
  3. 3. Effectiveness of Mouthrinse formulated from Aqueous Extract of Terminalia chebula on Salivary Streptococcus mutans Count and pH among 8- to 12-year-old School Children of Karnataka: A Randomized Clinical Trial. (2016)
  4. 4. Comparison of Antimicrobial Efficacy of (between) 0.2% Chlorhexidine and Herbal Mouthwash on Salivary Streptococcus mutans: A Randomized Controlled Pilot Study. (2018)
  5. 5. Evaluation of the Analgesic Activity of Standardized Aqueous Extract of Terminalia chebula in Healthy Human Participants Using Hot Air Pain Model. (2015)
  6. 6. A randomized, double-blind, placebo-controlled, cross-over study to evaluate analgesic activity of Terminalia chebula in healthy human volunteers using a mechanical pain model. (2016)
  7. 7. Randomized Double-Blind Placebo-Controlled Supplementation with Standardized Terminalia chebula Fruit Extracts Reduces Facial Sebum Excretion, Erythema, and Wrinkle Severity. (2023)
  8. 8. Effects of dietary supplementation with a standardized aqueous extract of Terminalia chebula fruit (AyuFlex®) on joint mobility, comfort, and functional capacity in healthy overweight subjects: a randomized placebo-controlled clinical trial. (2017)
  9. 9. Effects of plant extracts on patients with heart failure: a network meta-analysis of randomized controlled trials. (2025)
  10. 10. A randomized, double-blind, placebo-, and positive-controlled clinical pilot study to evaluate the efficacy and tolerability of standardized aqueous extracts of Terminalia chebula and Terminalia bellerica in subjects with hyperuricemia. (2016)

Generated August 14, 2026

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