Cocoa / Cacao

Cocoa / Cacao

Best for

Improve everyday quality of life

Not enough research · 10–635 mg/day for 4–26 weeks · 3 studies , n=225

43 papers · 2 claims · 107 outcomes scored · 2 positive

Outcomes

What cocoa / cacao actually does, by outcome

Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.

Outcome Effect Evidence Dose Weeks Rank
Sharpen focus and mental stamina Not enough research
trivial
5 RCTs n=266 20–681.4 g 4–4 wk
Improve everyday quality of life Not enough research
trivial
3 RCTs n=225 10–635 mg 4–26 wk

Risk profile

Adverse events and known drug interactions

Safety events

ischemic stroke severe
lower extremity revascularization moderate
foot infection moderate
urinary difficulty moderate
depression moderate
intolerance
constipation
headache

Co-studied with

Supplements that share evidence with cocoa / cacao

Sources

  1. 1. Dark Chocolate Intake May Reduce Fatigue and Mediate Cognitive Function and Gray Matter Volume in Healthy Middle-Aged Adults. (2022)
  2. 2. Cocoa Flavanols Improve Vascular Responses to Acute Mental Stress in Young Healthy Adults. (2021)
  3. 3. Cacao Polyphenol-Rich Dark Chocolate Intake Contributes to Efficient Brain Activity during Cognitive Tasks: A Randomized, Single-Blinded, Crossover, and Dose-Comparison fMRI Study. (2023)
  4. 4. The effects of dark chocolate on cognitive performance during cognitively demanding tasks: A randomized, single-blinded, crossover, dose-comparison study. (2024)
  5. 5. Cocoa-Rich Chocolate and Quality of Life in Postmenopausal Women: A Randomized Clinical Trial. (2020)
  6. 6. Effect of Cocoa Supplementation on the Biochemical and Clinical Profile and the Somatosensory Processing of Diabetic Peripheral and Autonomic Neuropathy: A Randomized Clinical Trial. (2025)
  7. 7. Everyday eating experiences of chocolate and non-chocolate snacks impact postprandial anxiety, energy and emotional states. (2012)
  8. 8. Cocoa Consumption Decreases Oxidative Stress, Proinflammatory Mediators and Lipid Peroxidation in Healthy Subjects: A Randomized Placebo-Controlled Dose-Response Clinical Trial. (2023)
  9. 9. Cocoa consumption for 2 wk enhances insulin-mediated vasodilatation without improving blood pressure or insulin resistance in essential hypertension. (2008)
  10. 10. Effects of Interval Jump Rope Exercise Combined with Dark Chocolate Supplementation on Inflammatory Adipokine, Cytokine Concentrations, and Body Composition in Obese Adolescent Boys. (2020)

Generated August 14, 2026

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