Alexandrian senna
Best for
Ease constipation and stay regular
Likely benefit · 15–1000 mg/day · 1 meta-analysis , n=254
1 papers · 1 claim · 1 outcomes scored · 1 positive
Outcomes
What alexandrian senna actually does, by outcome
Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.
Outcome Effect size Evidence Dose Weeks Rank
Ease constipation and stay regular Likely benefit
Softer stools, less straining, and more complete bowel movements.
1 meta-analysis n=254 15–1000 mg — #6/18
1 meta-analysis
n=254
Meta-analyzed
I²=99%
15–1000 mg
—
#6 /18
| Outcome | Effect | Evidence | Dose | Weeks | Rank |
|---|---|---|---|---|---|
| Ease constipation and stay regular Likely benefit | | 1 meta-analysis n=254 Meta-analyzed | 15–1000 mg | — | #6/18 |
Risk profile
Adverse events and known drug interactions
Safety events
flatulence mild
abdominal pain mild
headache mild
bloating mild
nausea and vomiting mild
diarrhea mild
various mild adverse events (diarrhea, acid regurgitation, nausea) mild
abdominal_pain
Sources
Generated August 14, 2026