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Tribulus

Tribulus

Best for

Increase sexual desire

Large effect, needs confirmation · 750–10500 mg/day for 4–13 weeks · 2 studies , n=120

8 papers · 3 claims · 34 outcomes scored · 3 positive

Outcomes

What tribulus actually does, by outcome

Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.

Outcome Effect Evidence Dose Weeks Rank
Increase sexual desire Large effect, needs confirmation
large 		2 RCTs n=120 750–10500 mg 4–13 wk #2/5
Improve erection quality Likely modest benefit
small 		1 meta-analysis n=272 Meta-analyzed 750–1500 mg — #2/8
Boost testosterone levels Barely detectable
trivial 		2 RCTs n=30 6–770 g 6–9 wk —
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Recommended Tribulus products

Real products that dose Tribulus where the research does, in a clean formulation, from brands we've audited. We only list ones we'd stand behind.

Chosen for adequate Tribulus dosing vs. the studied range, a clean formulation (grade A–C), and independent brand-quality audits. Not sponsored.

Risk profile

Adverse events and known drug interactions

Safety events

acute kidney injury severe
priapism severe
adrenal_insufficiency / HPA axis suppression severe
Cushingoid features (facial puffiness) moderate
weight_gain moderate
new-onset diabetes mellitus (HbA1c 6.5%) moderate
abdominal cramp mild
subclinical_hypothyroidism (TSH 7.19 µIU/mL, anti-TPO positive) mild

Drug interactions

Antidepressants major increases toxicity
Haloperidol moderate decreases effect
Cisplatin moderate decreases concentration
Metronidazole moderate decreases effect
other moderate increases concentration

Sources

  1. 1. Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use. (2023) ↑
  2. 2. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo - controlled study. (2014) ↑
  3. 3. Assessment of the Effects of Tribulus Terrestris on Sexual Function of Menopausal Women. (2016) ↑
  4. 4. Clinical study of Tribulus terrestris Linn. in Oligozoospermia: A double blind study. (2012) ↑
  5. 5. The Effects of 6 Weeks of Tribulus terrestris L. Supplementation on Body Composition, Hormonal Response, Perceived Exertion, and CrossFit® Performance: A Randomized, Single-Blind, Placebo-Controlled Study. (2021) ↑
  6. 6. 6-Week Supplementation with Tribulus terrestris L. to Trained Male CrossFit® Athletes on Muscle, Inflammation, and Antioxidant Biomarkers: A Randomized, Single-Blind, Placebo-Controlled Trial. (2022) ↑
  7. 7. Dietary Tribulus Terrestris as a functional food combined with blood flow restriction to enhance the jump performance of basketball athletes: a randomized crossover study. (2025) ↑
  8. 8. The effect of hydro-alcohol extract of Tribulus terrestris on sexual satisfaction in postmenopause women: A double-blind randomized placebo-controlled trial. (2018) ↑

Generated August 14, 2026

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