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Aloe

Aloe

Best for

Boost skin hydration

Likely modest benefit · 19 mcg/day for 4–12 weeks · 2 studies , n=163

9 papers · 2 claims · 20 outcomes scored · 2 positive

Outcomes

What aloe actually does, by outcome

Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.

Outcome Effect Evidence Dose Weeks Rank
Boost skin hydration Likely modest benefit
small 		2 RCTs n=163 19 mcg 4–12 wk #5/13
Boost skin radiance Faint early signal
small 		1 RCT n=47 40 mg 12 wk #1/3

Sources

  1. 1. In Vivo skin hydration and anti-erythema effects of Aloe vera, Aloe ferox and Aloe marlothii gel materials after single and multiple applications. (2014) ↑
  2. 2. Effects of low-dose Aloe sterol supplementation on skin moisture, collagen score and objective or subjective symptoms: 12-week, double-blind, randomized controlled trial. (2020) ↑
  3. 3. Antimicrobial Effects of Aloe Vera Mouthwash in Adults with Dental Caries: A Preliminary Clinical Trial. (2025) ↑
  4. 4. Preliminary antiplaque efficacy of aloe vera mouthwash on 4 day plaque re-growth model: randomized control trial. (2014) ↑
  5. 5. Comparison of Plaque Inhibiting Efficacies of Aloe Vera and Propolis Tooth Gels: A Randomized PCR Study. (2015) ↑
  6. 6. Improvement of glucose and lipid profile status with Aloe vera in pre-diabetic subjects: a randomized controlled-trial. (2015) ↑
  7. 7. Effects of 9 oral care solutions on the prevention of oral mucositis: a network meta-analysis of randomized controlled trials. (2020) ↑
  8. 8. The effect of different mouthwashes to prevent oral mucositis in patients with radiotherapy and chemotherapy: a network meta-analysis. (2025) ↑

Generated August 14, 2026

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