Hesperidin
Evidence status
Limited evidence to recommend for any consumer outcome yet.
13 papers · 0 claims · 46 outcomes scored
Recommended Hesperidin products
Real products that dose Hesperidin where the research does, in a clean formulation, from brands we've audited. We only list ones we'd stand behind.
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Nootropics Depot
Hesperidin Powder
Well dosed 500 mg/day A formulaBrand audit 87/100
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Nootropics Depot
Hesperidin Capsules 500 mg
Well dosed 500 mg/day A formulaBrand audit 87/100
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Bluebonnet
Citrus Bioflavonoid Complex 750 mg
Well dosed 750 mg/day B formulaBrand audit 82/100
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BulkSupplements.com
Hesperidin
Well dosed 500 mg/day A formulaBrand audit 54/100
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Doctor's Best
Hesperidin Methyl Chalcone 500 mg
Well dosed 500 mg/day C formulaBrand audit 82/100
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XYMOGEN
SynovX Al
Well dosed 469 mg/day C formulaBrand audit 80/100
Chosen for adequate Hesperidin dosing vs. the studied range, a clean formulation (grade A–C), and independent brand-quality audits. Not sponsored.
Risk profile
Adverse events and known drug interactions
Safety events
Drug interactions
Co-studied with
Supplements that share evidence with hesperidin
Sources
- 1. Effects of Citrus Flavanone Hesperidin Extracts or Purified Hesperidin Consumption on Risk Factors for Cardiovascular Disease: Evidence From an Updated Meta-analysis of Randomized Controlled Trials. (2024) ↑
- 2. Effects of 8 Weeks of 2S-Hesperidin Supplementation on Performance in Amateur Cyclists. (2020) ↑
- 3. Acute Effects of Hesperidin in Oxidant/Antioxidant State Markers and Performance in Amateur Cyclists. (2019) ↑
- 4. 8-Week Supplementation of 2S-Hesperidin Modulates Antioxidant and Inflammatory Status after Exercise until Exhaustion in Amateur Cyclists. (2021) ↑
- 5. Orange juice-derived flavanone and phenolic metabolites do not acutely affect cardiovascular risk biomarkers: a randomized, placebo-controlled, crossover trial in men at moderate risk of cardiovascular disease. (2015) ↑
- 6. Hesperetin-7-O-glucoside/β-cyclodextrin Inclusion Complex Induces Acute Vasodilator Effect to Inhibit the Cold Sensation Response during Localized Cold-Stimulate Stress in Healthy Human Subjects: A Randomized, Double-Blind, Crossover, and Placebo-Controlled Study. (2023) ↑
- 7. Effect of hesperidin on blood pressure and lipid profile: A systematic review and meta-analysis of randomized controlled trials. (2024) ↑
- 8. Hesperidin supplementation has no effect on blood glucose control: A systematic review and meta-analysis of randomized controlled clinical trials. (2020) ↑
- 9. The effects of hesperidin supplementation on insulin resistance and sensitivity in adults: a systematic review and meta-analysis of randomized controlled trials. (2025) ↑
- 10. Effect of Hesperidin as an Adjunct to Scaling and Root Planing on Clinical Parameters and Serum C-Reactive Protein Level in Chronic Periodontitis: A Randomized, Triple-Blind, Placebo-Controlled, Clinical Trial. (2024) ↑
Generated August 14, 2026