Pycnogenol
Best for
Boost skin hydration
Promising early signal · 150 mg/day for 26 weeks · 1 study , n=63
3 papers · 1 claim · 11 outcomes scored · 1 positive
Outcomes
What pycnogenol actually does, by outcome
Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.
Locks more moisture into skin so it feels softer and less tight.
| Outcome | Effect | Evidence | Dose | Weeks | Rank |
|---|---|---|---|---|---|
| Boost skin hydration Promising early signal | | 1 RCT n=63 | 150 mg | 26 wk | — |
Risk profile
Adverse events and known drug interactions
Drug interactions
Sources
- 1. An oral French maritime pine bark extract improves hair density in menopausal women: A randomized, placebo-controlled, double blind intervention study. (2023) ↑
- 2. Impact of Pycnogenol® Use in the Treatment of Patients With Lipedema: A Randomized Controlled Trial. (2025) ↑
- 3. Impact of a Dietary Supplementation with French Maritime Pine Bark Extract Pycnogenol® on Salivary and Serum Inflammatory Biomarkers During Non-Surgical Periodontal Therapy-A Randomized Placebo-Controlled Double-Blind Trial. (2025) ↑
Generated August 14, 2026
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