Artichoke
Best for
Ease indigestion and heartburn
Likely modest benefit · 1 meta-analysis , n=244
5 papers · 1 claim · 23 outcomes scored · 1 positive
Outcomes
What artichoke actually does, by outcome
Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.
Outcome Effect size Evidence Dose Weeks Rank
Ease indigestion and heartburn Likely modest benefit
Less upper-stomach heaviness, burning, and acid discomfort after eating.
1 meta-analysis n=244 — — #3/11
1 meta-analysis
n=244
Meta-analyzed
—
—
#3 /11
| Outcome | Effect | Evidence | Dose | Weeks | Rank |
|---|---|---|---|---|---|
| Ease indigestion and heartburn Likely modest benefit | | 1 meta-analysis n=244 Meta-analyzed | — | — | #3/11 |
Risk profile
Adverse events and known drug interactions
Safety events
abdominal_pain
Drug interactions
Doxorubicin moderate unknown
Drug:Fosfomycin moderate decreases effect
Fluconazole minor decreases concentration
other minor increases concentration
Sources
- 1. Non-Chinese herbal medicines for functional dyspepsia. (2023) ↑
- 2. The Effect of Artichoke Leaf Extract on Alanine Aminotransferase and Aspartate Aminotransferase in the Patients with Nonalcoholic Steatohepatitis. (2016) ↑
- 3. The Metabolic Effects of Cynara Supplementation in Overweight and Obese Class I Subjects with Newly Detected Impaired Fasting Glycemia: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial. (2020) ↑
- 4. Effects of Artichoke Supplementation on Liver Enzymes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. (2022) ↑
- 5. Anti-hypertensive Effects of Artichoke Supplementation in Adults: A Systematic Review and Dose-response Meta-analysis of Randomized Controlled Trials. (2022) ↑
Generated August 14, 2026
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