Guarana
Best for
Sharpen focus and mental stamina
Barely detectable · 125–1080 mg/day for 1 weeks · 3 studies , n=104
6 papers · 1 claim · 13 outcomes scored · 1 positive
Outcomes
What guarana actually does, by outcome
Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.
| Outcome | Effect | Evidence | Dose | Weeks | Rank |
|---|---|---|---|---|---|
| Sharpen focus and mental stamina Barely detectable | | 3 RCTs n=104 | 125–1080 mg | 1 wk | — |
Recommended Guarana products
Real products that dose Guarana where the research does, in a clean formulation, from brands we've audited. We only list ones we'd stand behind.
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Nature's Answer
Guarana 1,000 mg
Well dosed 3,000 mg/day A formulaBrand audit 75/100
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Nutricost
Guarana Powder 1 g
Well dosed 1,000 mg/day A formulaBrand audit 57/100
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BulkSupplements.com
Guarana Extract
Well dosed 1,000 mg/day A formulaBrand audit 54/100
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Nutricost
Guarana 1 g
Well dosed 1,000 mg/day B formulaBrand audit 57/100
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Source Naturals
Guarana Energizer 900 mg
Well dosed 2,700 mg/day C formulaBrand audit 73/100
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Swanson
Full Spectrum Guarana 500 mg
Well dosed 3,000 mg/day C formulaBrand audit 69/100
Chosen for adequate Guarana dosing vs. the studied range, a clean formulation (grade A–C), and independent brand-quality audits. Not sponsored.
Risk profile
Adverse events and known drug interactions
Safety events
Drug interactions
Sources
- 1. Effects of a commercial product containing guaraná on psychological well-being, anxiety and mood: a single-blind, placebo-controlled study in healthy subjects. (2013) ↑
- 2. Cognitive effects of guarana supplementation with maximal intensity cycling. (2023) ↑
- 3. Effects of Acute Guarana (Paullinia cupana) Ingestion on Mental Performance and Vagal Modulation Compared to a Low Dose of Caffeine. (2024) ↑
- 4. Natural supplementation to effectively treat cancer-induced fatigue: evidence of a meta-analysis on the use of guaraná. (2024) ↑
- 5. Effect of Guarana (Paullinia cupana) on Cognitive Performance: A Systematic Review and Meta-Analysis. (2023) ↑
- 6. The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials. (2025) ↑
Generated August 14, 2026
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