Resveratrol

Best for

Reduce fine lines and wrinkles

Promising early signal · 150 mg/day for 8 weeks · 1 study , n=60

71 papers · 5 claims · 181 outcomes scored · 5 positive

Outcomes

What resveratrol actually does, by outcome

Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.

Outcome Effect size Evidence Dose Weeks Rank

Reduce fine lines and wrinkles Promising early signal

Smooths crow's feet, forehead lines, and surface roughness.

1 study n=60 150 mg 8 wk #4/5

41488277

moderate

1 study n=60

150 mg

8 wk

#4 /5

Lower your blood pressure Likely modest benefit

Brings down both systolic and diastolic, especially when baseline runs high.

15 meta-analyses n=4.0k 8.1–3000 mg 4–14 wk

22055504·23193181·24073011·24866496 +11 more

small

15 meta-analyses n=4.0k Meta-analyzed

8.1–3000 mg

4–14 wk

—

Lower bad and total cholesterol Studies contradict

Cuts the cholesterol that builds into artery plaque over time.

20 meta-analyses n=8.8k 10–3000 mg/kg 4–26 wk #7/103

24073011·27560482·28329397·28505227 +16 more

trivial

20 meta-analyses n=8.8k Meta-analyzed I²=98%

10–3000 mg/kg

4–26 wk

#7 /103

Slow biological aging markers Not enough research

Your body's internal age trends younger than the calendar predicts.

2 meta-analyses n=632 40–3000 mg 14–26 wk #1/2

29330620·40158656

trivial

2 meta-analyses n=632 Meta-analyzed I²=81%

40–3000 mg

14–26 wk

#1 /2

Keep arteries flexible Not enough research

Artery walls that stretch and recoil absorb each heartbeat smoothly.

3 RCTs n=138 150–500 mg 4–4 wk

28604618·34073163·37447275

trivial

3 RCTs n=138

150–500 mg

4–4 wk

—

Outcome	Effect	Evidence	Dose	Weeks	Rank
Reduce fine lines and wrinkles Promising early signal	moderate	1 study n=60	150 mg	8 wk	#4/5
Lower your blood pressure Likely modest benefit	small	15 meta-analyses n=4.0k Meta-analyzed	8.1–3000 mg	4–14 wk	—
Lower bad and total cholesterol Studies contradict	trivial	20 meta-analyses n=8.8k Meta-analyzed	10–3000 mg/kg	4–26 wk	#7/103
Slow biological aging markers Not enough research	trivial	2 meta-analyses n=632 Meta-analyzed	40–3000 mg	14–26 wk	#1/2
Keep arteries flexible Not enough research	trivial	3 RCTs n=138	150–500 mg	4–4 wk	—

Buy well

Recommended Resveratrol products

Real products that dose Resveratrol where the research does, in a clean formulation, from brands we've audited. We only list ones we'd stand behind.

Chosen for adequate Resveratrol dosing vs. the studied range, a clean formulation (grade A–C), and independent brand-quality audits. Not sponsored.

Risk profile

Adverse events and known drug interactions

Safety events

nephrotoxicity severe

Nephrotoxicity severe

Cardiac inflammation severe

Renal tubular necrosis severe

Urinary tract infection (hospitalisation) severe

Bowel blockage (hospitalisation) severe

Oesophageal tear repair (hospitalisation) severe

Pre-scheduled lumbar spine operation (hospitalisation) severe

Drug interactions

Paclitaxel major decreases effect

Cyclosporine major increases concentration

Midazolam major increases concentration

Drug:Warfarin major increases effect

Antidepressants major increases toxicity

other major increases effect

Warfarin major increases effect

Methotrexate major increases concentration

other major decreases effect

Bortezomib major unknown

Co-studied with

Supplements that share evidence with resveratrol

Sources

Generated August 14, 2026

Resveratrol

What resveratrol actually does, by outcome

Recommended Resveratrol products

Adverse events and known drug interactions

Supplements that share evidence with resveratrol

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Resveratrol

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