Punicalagin
Best for
Lower your blood pressure
Faint early signal · 538.37 mg/day for 8 weeks · 1 study , n=54
5 papers · 1 claim · 20 outcomes scored · 1 positive
Outcomes
What punicalagin actually does, by outcome
Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.
Outcome Effect size Evidence Dose Weeks Rank
Lower your blood pressure Faint early signal
Brings down both systolic and diastolic, especially when baseline runs high.
1 RCT n=54 538.37 mg 8 wk #5/81
1 RCT
n=54
538.37 mg
8 wk
#5 /81
| Outcome | Effect | Evidence | Dose | Weeks | Rank |
|---|---|---|---|---|---|
| Lower your blood pressure Faint early signal | | 1 RCT n=54 | 538.37 mg | 8 wk | #5/81 |
Risk profile
Adverse events and known drug interactions
Safety events
gastrointestinal events (bloating, diarrhoea, nausea, abdominal pain, constipation) mild
Sources
- 1. Effect of pomegranate extract on blood pressure and anthropometry in adults: a double-blind placebo-controlled randomised clinical trial. (2017) ↑
- 2. Pomegranate Extract Improves Maximal Performance of Trained Cyclists after an Exhausting Endurance Trial: A Randomised Controlled Trial. (2019) ↑
- 3. Prospective Randomized Double-Blind Placebo-Controlled Study of Oral Pomegranate Extract on Skin Wrinkles, Biophysical Features, and the Gut-Skin Axis. (2022) ↑
- 4. Prospective Randomized, Double-Blind, Placebo-Controlled Study of a Standardized Oral Pomegranate Extract on the Gut Microbiome and Short-Chain Fatty Acids. (2023) ↑
- 5. Antioxidant Properties and Beneficial Cardiovascular Effects of a Natural Extract of Pomegranate in Healthy Volunteers: A Randomized Preliminary Single-Blind Controlled Study. (2022) ↑
Generated August 14, 2026