phosphatidylcholine
Evidence status
Limited evidence to recommend for any consumer outcome yet.
9 papers · 0 claims · 24 outcomes scored
Recommended phosphatidylcholine products
Real products that dose phosphatidylcholine where the research does, in a clean formulation, from brands we've audited. We only list ones we'd stand behind.
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Seeking Health
Optimal PC
Well dosed 800 mg/day A formulaBrand audit 85/100
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Allergy Research Group
Phosphatidyl Choline
Well dosed 4.62 Gram(s)/day A formulaBrand audit 83/100
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Designs for Health
Phosphatidylcholine
Well dosed 4,000 mg/day A formulaBrand audit 80/100
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Double Wood Supplements
Phosphatidyl Choline 1200 mg
Well dosed 1,200 mg/day A formulaBrand audit 75/100
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Carlson
Phosphatidyl Choline
Well dosed 1,200 mg/day A formulaBrand audit 83/100
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XYMOGEN
PhosphaLine
Well dosed 2.7 Gram(s)/day A formulaBrand audit 80/100
Chosen for adequate phosphatidylcholine dosing vs. the studied range, a clean formulation (grade A–C), and independent brand-quality audits. Not sponsored.
Risk profile
Adverse events and known drug interactions
Safety events
Drug interactions
Sources
- 1. The impact of choline supplementation on oxidative stress and clinical outcomes among patients with non-alcoholic fatty liver disease: a randomized controlled study. (2025) ↑
- 2. Dietary Choline and Betaine and Risk of CVD: A Systematic Review and Meta-Analysis of Prospective Studies. (2017) ↑
- 3. Common genetic polymorphisms define one-carbon metabolite responses to different forms of choline in healthy adult males. (2025) ↑
- 4. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. (2013) ↑
- 5. Association between Maternal Choline, Fetal Brain Development, and Child Neurocognition: Systematic Review and Meta-Analysis of Human Studies. (2022) ↑
- 6. Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis. (2005) ↑
- 7. Delayed-Release Phosphatidylcholine Is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. (2021) ↑
- 8. Dietary Choline Supplements, but Not Eggs, Raise Fasting TMAO Levels in Participants with Normal Renal Function: A Randomized Clinical Trial. (2021) ↑
- 9. First multicenter study of modified release phosphatidylcholine "LT-02" in ulcerative colitis: a randomized, placebo-controlled trial in mesalazine-refractory courses. (2014) ↑
Generated August 14, 2026
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