Stinging Nettle
Best for
Lower your blood pressure
Promising early signal · 300 mL/day for 16 weeks · 1 study , n=15
5 papers · 2 claims · 22 outcomes scored · 2 positive
Outcomes
What stinging nettle actually does, by outcome
Each row is one outcome with effect size, evidence base, the dose that worked in trials, and time to first effect. Magnitude tiers come from native-unit MCID where available, Cohen's d otherwise.
Outcome Effect size Evidence Dose Weeks Rank
Lower your blood pressure Promising early signal
Brings down both systolic and diastolic, especially when baseline runs high.
1 RCT n=15 300 mL 16 wk
1 RCT
n=15
300 mL
16 wk
—
Ease seasonal allergy symptoms Faint early signal
Breathe easier and sneeze less during pollen season.
1 RCT n=40 150 mg 4 wk #4/7
1 RCT
n=40
150 mg
4 wk
#4 /7
| Outcome | Effect | Evidence | Dose | Weeks | Rank |
|---|---|---|---|---|---|
| Lower your blood pressure Promising early signal | | 1 RCT n=15 | 300 mL | 16 wk | — |
| Ease seasonal allergy symptoms Faint early signal | | 1 RCT n=40 | 150 mg | 4 wk | #4/7 |
Risk profile
Adverse events and known drug interactions
Safety events
urticaria (skin burning/stinging sensation) mild
Diarrhea
Elevated creatine kinase
Headache
contact dermatitis
urticaria
hypersensitivity
diarrhoea
Drug interactions
Anxiolytics moderate increases effect
Lorazepam moderate increases effect
Phenobarbital moderate increases effect
Clonazepam moderate increases effect
Zolpidem moderate increases effect
Antithrombotic Agents moderate unknown
Blood Glucose Lowering moderate increases effect
Diuretics moderate increases effect
Ace Inhibitors And Arbs moderate increases effect
Antineoplastic Agents minor unknown
Sources
- 1. Efficacy of Supportive Therapy of Allergic Rhinitis by Stinging Nettle (Urtica dioica) root extract: a Randomized, Double-Blind, Placebo- Controlled, Clinical Trial. (2017) ↑
- 2. Antihypertensive Indigenous Lebanese Plants: Ethnopharmacology and a Clinical Trial. (2019) ↑
- 3. Effects of Urtica dioica supplementation on blood lipids, hepatic enzymes and nitric oxide levels in type 2 diabetic patients: A double blind, randomized clinical trial. (2016) ↑
- 4. Comparison of the Effect of Cumin Cyminum and Nettle Oral Drops on the Breast Milk Sufficiency Indicators in New Mothers. (2024) ↑
- 5. A Placebo-Controlled, Pseudo-Randomized, Crossover Trial of Botanical Agents for Gulf War Illness: Reishi Mushroom (Ganoderma lucidum), Stinging Nettle (Urtica dioica), and Epimedium (Epimedium sagittatum). (2021) ↑
Generated August 14, 2026